PUER Platter: Snapper or Seabass for Supper?
“There are so many diets and dietary recommendations out there… Which one is right for me?”
Health professionals widely agree on the fundamental elements of a healthy diet - Eat more fruits, vegetables, whole grains, legumes, lean proteins, and healthy fats, and fewer ultra-processed foods high in added sugars and salt. However, emerging research underscores the fact that individuals exhibit unique responses to the same foods, suggesting that a one-size-fits-all approach to nutrition may not be ideal for everyone.
In the pursuit of optimal health, well-being, and longevity, precision nutrition is emerging as a promising new frontier. At the forefront is the personalised diet, which tailors nutrition recommendations to an individual's unique genetic makeup, molecular profile and our guest, the microbiome. This personalised approach recognises that each person’s biology is unique, necessitating customised dietary and lifestyle interventions.
PUER paves the path: as the bespoke and most scientific multigenerational concierge program for health, wellness, and longevity, PUER takes out the guesswork from finding the most suitable diet and lifestyle regimen for its members. Leveraging cutting-edge technologies in genomics, molecular medicine, and comprehensive imaging, PUER conducts thorough biological assessments for each member, paving the way for personalised health interventions.
At the heart of PUER’s approach lies multiomic medicine, a revolutionary framework that integrates data from multiple biological levels to fine-tune dietary and exercise recommendations. Multiomic medicine utilises insights from various ‘omics’ fields, including genomics, methylomics, proteomics, glycomics and metabolomics, to paint a comprehensive picture of an individual’s physiology, metabolism, and dietary responses.
Genomics plays a pivotal role in precision nutrition by uncovering genetic predispositions that influence how individuals metabolise nutrients, their susceptibility to certain diseases, and their unique dietary requirements. With this knowledge, personalised dietary recommendations can be crafted to optimise health outcomes and mitigate disease risks. For example, if you were born with certain variations in your APOA5 gene, a key regulator of blood lipid levels, the amount and type of fat that you eat each day may be particularly important for maintaining a healthy lipid profile and preventing heart disease. For example, you may want to include more fatty fish like herring or salmon.
Proteomics further enhances personalised nutrition by exploring the expression and function of proteins, providing valuable insights into cellular processes and responses to dietary interventions. For instance, cruciferous vegetables (e.g. broccoli, Brussels sprouts, cabbage) contain sulphoraphane. Increasing consumption of these foods in the diet can reduce oxidative stress by enhancing the activity of key enzymes involved in the production of glutathione, which is a critical antioxidant in the body. Integrating data from these ‘omics’ disciplines allows for the development of personalised diets tailored to an individual’s unique biological makeup and health goals.
The personalised diets and exercise programs informed by the multiomics approach is at the core of PUER.
Metabolomics complements genomics, proteomics and other ‘omics’ by examining the metabolites present in the body, providing real-time snapshots of metabolic processes. By analysing metabolic profiles, researchers can identify metabolic imbalances, nutrient deficiencies, and metabolic pathways influenced by diet. This information enables the formulation of targeted dietary strategies to support metabolic health and optimise energy levels. Since PUER measures thousands of metabolites from your body, it takes all guesswork out of dietary supplements. Your dietary supplements are no longer dictated by what is trending on TikTok on any given day, rather, by your own, unique metabolic profiles. For example, if your blood levels of beta-carotene are low, you should consider eating more vibrantly colored orange vegetables, such as carrots and sweet potatoes, to increase your levels of this potent antioxidant.
Microbiomics, the study of the microbiome - the diverse community of microorganisms residing in the gut - adds another layer of complexity to personalised nutrition. The composition of gut bacteria impacts digestion, nutrient absorption, metabolism, and immune function. Through microbiome analysis, scientists can identify personalised dietary interventions to promote gut health and overall well-being.
The personalised diets and exercise programs informed by the multiomics approach is at the core of PUER. By harnessing the power of genomic, microbiomic, metabolomic, and proteomic data, along with other markers, these diets offer targeted solutions to optimise health, prevent disease, enhance longevity, and improve overall well-being at an individualised level.
As our understanding of human biology continues to advance, the potential for personalised nutrition to transform health outcomes grows. PUER stands at the forefront of this transformative movement, empowering individuals to take control of their health through precision-based dietary interventions tailored to their specific biological needs.
Enjoy your snapper! (or seabass, whichever is best for YOU!)
For more information about PUER, click here.
